Home >> Product >> Biochemicals >> N-Ethoxycarbonyl-2-ethoxy-1,2- ...
←Return Back
  • Product Name:   N-Ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline
  • Synonyms:   Ethyl 2-ethoxy-1,2-dihydro-1-quinolinecarboxylate for synthesis;ethyl N-(2-ethoxy-1,2-dihydroquinoline)carboxylate;EEDQ (1-ETHOXY-CARBONYL-2-ETHOXY-1,2;EEDQ, 99+%, (2-ETHOXY-1-ETHOXYCARBONYL-1 ,2-DIHYDROQUINOLINE);Eedq(2-Ethoxy-1-Ethoxycarbonyl-1,2-Dihydroquinoline)
  • CAS No.:   16357-59-8
  • Molecular Formula:   C14H17NO3
  • Molecular Weight :   247.29
  • Specification :   98%
  • Place of Origin:   China
  • Appearance :   
  • Document :   Download

Description of N-Ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline
N-Ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline Chemical Properties
Melting point  62-67 °C(lit.)
Boiling point  125-128 °C (0.1 mmHg)
density  1.1173 (rough estimate)
refractive index  1.5300 (estimate)
Fp  125-128°C/0.1mm
storage temp.  2-8°C
form  Crystalline Powder
color  White to beige
Water Solubility  insoluble
Sensitive  Moisture Sensitive
Merck  14,3518
BRN  533048
CAS DataBase Reference 16357-59-8(CAS DataBase Reference)
EPA Substance Registry System 1(2H)-Quinolinecarboxylic acid, 2-ethoxy-, ethyl ester(16357-59-8)
Safety Information
Hazard Codes  Xi,Xn
Risk Statements  38-36/37/38-20/21/22
Safety Statements  22-24/25-36/37/39-26-36
WGK Germany  3
RTECS  VB2010000
F  9-21
TSCA  Yes
HS Code  29334990
N-Ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline Usage And Synthesis
Chemical Properties White to pale yellow solid
Uses Peptide condensing agent with little or no racemization. Amidation coupling reagent.
Uses In the synthesis of peptides.
Purification Methods Dissolve EEDQ ~180g in CHCl3, evaporate to dryness in a vacuum. Add dry Et2O (20mL) and a white solid separates on standing. Set aside for a few hours, collect the solid, wash it thoroughly with cold Et2O and dry it in a vacuum (~140g, m 63.5-65o). A further crop of solid (~25g) is obtained from the filtrate on standing overnight. [Fieser & Fieser Reagents for Organic Synthesis 2 191 1969, Belleau et al. J Am Chem Soc 90 823 1968 and 90 1651 1968, Beilstein 21/3 V 28.]
N-Ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline Preparation Products And Raw materials
Raw materials Diethyl ether-->Dichloromethane-->N,N-Dimethylformamide-->Magnesium sulfate-->Potassium hydroxide -->Ethyl chloroformate-->Quinoline-->Boron trifluoride etherate

  Please leave your message to us :

    ( Your Information is an important part of our business,and we will not share or sell any of it to anyone.)

 
Your Name:
Email:
Product: N-Ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline
Message:
 

N-Ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline related products :

HOTU |HATU |HBTU |(Benzotriazol-1-yloxy)dipyrrolidinocarbenium hexafluorophosphate |5-Chloro-1-[bis(dimethylamino)methylene]-1H-benzotriazolium 3-oxide hexafluorophosphate |HDBTU |HNTU |HOAt |N-Hydroxy-5-norbornene-2,3-dicarboximide |HPTDP |HPTU |Dipyrrolidino(N-succinimidyloxy)carbenium hexafluorophosphate |N,N,N',N'-Tetramethyl-O-(N-succinimidyl)uronium hexafluorophosphate |N,N,N',N'-Tetramethyl-S-(1-oxido-2-pyridyl)thiuronium hexafluorophosphate |Ethyl 1-hydroxy-1H-1,2,3-triazole-4-carboxylate |mono-Methyl terephthalate |4-(4,6-Dimethoxy-1,3,5-triazin-2-yl)-4-morpholinium tetrafluoroborate |N-Hydroxysuccinimide |Chlorodipiperidinocarbenium hexafluorophosphate |(3-Hydroxy-3H-1,2,3-triazolo[4,5-b]pyridinato-O)tri-1-pyrrolidinylphosphonium hexafluorophosphate |Benzotriazole-1-yl-oxytripyrrolidinophosphonium hexafluorophosphate |Bromo-tris-pyrrolidino-phosphonium hexafluorophosphate |1-(Chloro-1-pyrrolidinylmethylene)pyrrolidinium hexafluorophosphate |Chlorotripyrrolidinophosphonium hexafluorophosphate |2-(7-Azabenzotriazole-1-yl)-1,1,3,3-tetramethyluronium tetrafluoroborate |2-(1H-Benzotriazole-1-yl)-1,1,3,3-tetramethyluronium tetrafluoroborate |O-(6-Chlorobenzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate |N,N,N',N'-Tetramethyl-O-(3,4-dihydro-4-oxo-1,2,3-benzotriazin-3-yl)uronium tetrafluoroborate |Fluoro-N,N,N',N'-tetramethylformamidinium hexafluorophosphate |3,4,5,6-Tetrahydro-1,3-dimethyl-2-[(1-oxido-2-pyridinyl)thio]pyrimidinium tetrafluoroborate |2-(2-Pyridon-1-yl)-1,1,3,3-tetramethyluronium tetrafluoroborate |1-(p-Toluenesulfonyl)-3-nitro-1,2,4-triazole |TSTU |2,4,6-Triisopropylbenzene-sulfonyl azide |Propylphosphonic anhydride |BIS(4-NITROPHENYL) CARBONATE |2-Chloro-4,6-dimethoxy-1,3,5-triazine |BIS(PENTAFLUOROPHENYL)CARBONATE |2-Chloro-1,3-dimethylimidazolidinium chloride |2-Pyridinol-1-oxide |

Products

Contact Us

  • Email: info@vosunbio.com
  • Tel:+86-512-66566131,89888618
  • sales extension 8002