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  • Product Name:   Pyridazine
  • Synonyms:   1,2-Diazabenzene;o-diazine;Pyridazin;1,2-DIAZINE;AKOS 92457
  • CAS No.:   289-80-5
  • Molecular Formula:   C4H4N2
  • Molecular Weight :   80.09
  • Specification :   98%
  • Place of Origin:   China
  • Appearance :   
  • Document :   Download

Description of Pyridazine



Pyridazine Chemical Properties


Melting point  −8 °C(lit.)


Boiling point  208 °C(lit.)


density  1.103 g/mL at 25 °C(lit.)


refractive index  n20/D 1.524(lit.)


Fp  185 °F


storage temp.  Refrigerator


pka 2.24(at 20℃)


form  Liquid


color  Clear yellow-brown


Water Solubility  MISCIBLE


Merck  14,7969


BRN  103906


CAS DataBase Reference 289-80-5(CAS DataBase Reference)


NIST Chemistry Reference Pyridazine(289-80-5)




Safety Information


Hazard Codes  Xn


Risk Statements  36/37/38-22


Safety Statements  23-24/25


RIDADR  NA 1993 / PGIII


WGK Germany  3


RTECS  UR5267000


8-10


TSCA  Yes




Pyridazine Usage And Synthesis


Heterocyclic compound Pyridazine refers to a heterocyclic azine compound containing a nitrogen hexaheterocyclic , it and pyrimidine, pyrazine are isomers of each other , it is insoluble in petroleum ether, soluble in methanol, ethanol and ether, and it can be miscible with water, benzene and dimethyl formamide immiscibility. Pyridazine is a weak base, which can form salts with picric acid, and hydrochloric acid; pyridazine is not prone to nucleophilic and electrophilic aromatic substitution reaction; it is stable to potassium permanganate; sodium or alcohols may be reduced open-chain , and converted to 1,4-diaminobutane. Pyridazine is widely used as pharmaceutical raw materials, such as long-term sulfa SMP which is pyridazine derivative, 4-amino-cinnoline which belongs to antimalarials, blood pressure drug hydralazine, etc. all use pyridazine as raw materials; it can also be used as raw material of pesticides, for the production of herbicides, "herbicide-sensitive", "Milstem", "bromine herbicide-sensitive", "Kusakira," "maleic hydrazide", "Norflurazon", "pyridate "" insecticide "," imputed phosphorus "and so on.
The above information is edited by the chemicalbook of Tian Ye.


Chemical Properties Clear yellowish-brown liquid




Pyridazine Preparation Products And Raw materials


Preparation Products Cefozopran-->Levosimendan-->Pyridat-->Bazinaprine


Raw materials Hydrazine hydrate-->2,5-Dihydro-2,5-dimethoxyfuran


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